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The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. [16] in a systematic review in 2015. 2018;2018:110. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial, https://doi.org/10.1186/s12903-021-01864-x, https://clinicaltrials.gov/ct2/show/NCT04249336, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Pro-argin resulted in the immediate treatment response and statistically significant (p<0.001) clinical reduction in DH than FCPS in the present study, as shown in Table 3. Provides 24/7 sensitivity protection. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. Grading of Recommendations, Assessment, Development and Evaluations. The makers of Colgate Sensitive Pro-Relief and its rival, Sensodyne Rapid Relief, have been dobbing each other into the health regulator over advertising claims that the toothpastes give users "instant" relief to pain from sensitive teeth. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). Am J Dent. For lsting relief, apply to a gentle toothbrush making sure to brush all . Read our disclaimer for details. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. J Clin Dent 20 (2009), special issue 123-130, 2. Colgate Total with stannous fluoride also offers more benefits than ever before, including sensitivity relief, improved enamel strength* and odor neutralization* (*based on in vitro studies).Colgate Total Advanced Whitening is a tooth whitening toothpaste that provides stain removal and prevention. The Pro-Argin technology repairs sensitive areas of the teeth for instant* and long-lasting sensitivity pain relief. Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. Article Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. in 2019 using BioMin F and Pro-argin. 2017;71:18. A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. Colgate Sensitive Pro-Relief Enamel Rebuild also: Fights cavities Strengthens enamel Freshens breath Vegan . It also strengthens tooth enamel by helping rebuild weak spots. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . SJAZ has contributed to the conception, design, interpretation of results and critically revised the manuscript. volume21, Articlenumber:498 (2021) Innehll Colgate Sensitive Instant Relief Enamel Repair r en fluortandkrm med Pro-Argin-teknologi som ger omedelbar smrtlindring vid ilningar i tnderna. BMC Oral Health Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. Colgate Sensitive PRO-Relief provides you relief from sudden shocks of pain and long-term sensitivity with regular use. [22] reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Use regularly to enjoy long-lasting relief from sensitivity*. Oral dentifrices have been marketed for pain relief within a minute for DH. WHAT IS THE FLUORIDE CONTENT OF Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE? Ingredients *Calcium carbonate *Water Hines D, Rinaudi L, Xu S, Lavender S, Pilch S: The Use of Confocal Laser Scanning Microscopy and a Novel Imaging Program for Quantifying Dentine Tubule Occlusion. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. 2. Compend Contin Educ Dent. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? Colgate-Palmolive Company 2018. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. [9] stated in 2017 that arginine and strontium acetate-based desensitisers had equal clinical significance in reducing pain in DH and the other findings of the meta-analysis suggested that strontium acetate and Pro-argin should be compared for clinical efficacy immediately after topical application by independent health authorities. Though all bioactive agents have a significant treatment effect in reducing DH, there is currently no consensus on the unequivocal efficacy of any product or bioactive agent used for managing the condition due to huge variations and heterogeneity in the conduct of clinical trials on DH [6]. 2. 2019;46(12):11216. Provided by the Springer Nature SharedIt content-sharing initiative. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Dent Health Curr Res. This binds to the negatively charged dentine surface like a magnet. Colgate Sensitive Pro-Relief Original Toothpaste This toothpaste gives you the freedom to forget about tooth sensitivity. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. Docimo R et al. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. Brush twice daily. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. We found more change in pain scores of VAS used for mechanical stimuli with Pro-argin than FCPS as shown in Table 5 that could be relatable with a randomised controlled trial of FCPS and arginine based desensitizers reporting better treatment response of arginine than FCPS in the cold stimulated DH after two weeks to one month, subsequently [40]. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. 2009; 20 (Spec Iss): 1722. J Oral Rehabil. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. The formula consists of Arginine, an amino acid naturally found in saliva and also calcium from calcium carbonate. Arshad, S., Zaidi, S.J.A. Yes, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste should be used for twice daily toothbrushing to provide ongoing relief from the pain of sensitive teeth. Another study by Hines et al. Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. Anvnd tv gnger dagligen. ^Vs novamin/sodium fluoride technology and stannous fluoride/sodium fluoride technology (p<0.05). If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Dentine hypersensitivity. 1. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. I am interested to hear you guys opinion and thought about it. The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. Colgate-Palmolive Company 2018. Privacy Ashwini S, Swatika K, Kamala DN. Pessoa OF, Loretto SC, Maia LC. 2020;99(5):51422. A total of 128 participants completed the trial. 2016;8:114. These dentifrices were extracted in a plain tube by the dental assistant from commercial packing and labelled with treatment codes to keep the principal investigator and participants blinded at the time of treatment assignment. Effect of dentin hypersensitivity treatment on oral health related quality of lifea systematic review and meta-analysis. The effect of the incorporation of fluoride into strontium containing bioactive glasses. All the treatment groups showed statistically significant improvement in DH with p<0.001 relative to baseline at all time points. 2019;40(10):6537 (quiz 8). [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. Clinically proven lasting relief for 8 weeks. Colgate Sensitive Pro-Relief toothpastes have been formulated to provide instant and lasting relief from the pain associated with sensitive teeth. Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. There was a significant (p<0.001) reduction of 45.7% with Pro-argin, 37.6% with 8% strontium acetate, 18.1% with FCPS, and 15.2% with NaF-based dentifrices relative to baseline on SCASS after one-minute application on sensitive teeth. IADR, The Excel, United Kingdom. These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. Made by one of the best-known oral care companies in Australia, it has been clinically proven to provide both instantaneous and lasting relief from sensitivity, whilst also: Fighting cavities. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. Find products and services. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. Pro-Argin technology helps to seal and repair . Plus it has the freshness you trust from Colgate! Klubpris: 25,46 kr. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. 2008;29(8):1S-35S. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke Balevi B. Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. With regular use, the Pro-Argin formula builds a long-lasting protective barrier that acts like a seal against sensitivity. Poster #3406, July 2018 IADR. Tandkrmen har ett slipmedel som ger en mild polering och tar bort yttre flckar och fluor skyddar tnderna mot karies. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. Lasting relief with 2x daily continued brushing. was used for statistical analysis. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. No side effects, apart from money not well spent. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. It is clinically proven for instant and lasting Sensitivity relief* How does it work? Gentle whitening formula. 2010;21(2):568. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. PubMed Central The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. The limitation of our study is that fluoridated dentifrice was used as a control which, although regarded as not possessing any desensitising effects. Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. For lasting relief and gum protection, apply twice daily using a sensitive toothbrush, making sure to brush all surfaces of teeth including sensitive areas. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). Pak Oral Dent J. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. Pro-Argin technology is occlusive. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste with Pro-Argin Technology and Zinc. Blocks the pain of sensitive teeth. 4Intervention D denotes Colgate Total. & Farooqui, W.A. Am J Dent. . The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. It was found statistically significant relative to control on all clinical parameters of the SCASS and VAS. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. Effect of desensitizing toothpastes on dentine hypersensitivity: a systematic review and meta-analysis. Mahmoodi B, Wood R, Cook R. Protection and acid resistivity of bioactive-glasses, arginine and calcium silicate. Correspondence to In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). 2019;81:16. Am J Dent. Hence, the current study outcomes, along with previously published findings, corroborate the in vitro findings of obliteration of dentinal tubules with strontium acetate impeding painful fluid movement in dentine [29]. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. While FCPS in BioMin F can be the best possible treatment option for long-term management of DH in the form of OTC dentifrices. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. This clinical trial has not included a run-in or washout period before the test phase due to time constraints and compliance of the potential participants. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. 1997;24(11):80813. Moreover, FCPS as a new bioactive material revealed promising potency of sustainable management of DH in a previously conducted trial by Ashwini et al. 1):8A-15A. This toothpaste prevents sensitivity coming back by building a protective barrier that acts like . For best performance, keep cap closed when not in use. Colgate Sensitive Instant Relief Toothpaste starts blocking sensitivity pain instantly*. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. Zang P, Shaw D. A randomized clinical study to evaluate the efficacy of an 8%(w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. Last updated on May 11, 2021. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. 2 Docimo et al. 2015;28(1):404. 2018. It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. There is no problem with every day and prolonged use. Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. da Cruz LPD, Hill RG, Chen X, Gillam DG. Plain bi-carb soda and coconut butter do a far better job at cleaning and desensitising. This toothpaste really does not help at all with symptoms of sensitive teeth. HOW DOES Colgate SENSITIVE INSTANT Relief Repair & Prevent WORK? Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Sealed channels protect against pain caused by hot, cold and sweet stimuli. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. This toothpaste contains a unique formula that blocks the pathways to pain instantly Its clinically proven formula provides INSTANT RELIEF from the first usage, LONG-LASTING RELIEF with twice everyday use. However, strontium acetate can potentially obliterate dentinal tubules by replacing the calcium ions of hydroxyapatite crystal lattice structure withstrontium ions along with its nerve depolarisation treat DH [7]. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. 1997;24(11):80813. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. [18] in a meta-analysis in 2020. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. Dentine tubule occlusion by novel bioactive glass-based toothpastes. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 4 Hines D et al. Identifier NCT 04249336. PubMed For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. Colgate Sensitive Instant Relief Whitening Toothpaste 75 ml Pack of 5, Blocks Pain Instantly, Prevents Sensitivity, Gently Removes Stains (5 x 75 ml) 1,230 5 offers from 12.50 Colgate Sensitive Pro Relief Enamel Repair Toothpaste 75ml - 4 packs 94 22 offers from 14.14 Colgate Sensitive Instant Relief Enamel Repair Toothpaste 75 ml 190 Another meta-analysis by Hu et al. blokerer jeblikkeligt smerter fra isninger. https://doi.org/10.17352/2394-8418.00003. J Clin Dent. Then, the repeated measure was obtained after five minutes for previous pain recovery, and dentifrices were provided to the patient for self-application. Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). 90 sold. See patient relevant information on Colgate.com. 3 Report Deon Hines-0003, 2016. Identifier NCT 04249336. Colgate Sensitive Pro Relief Teeth Whitening Sensitivity Toothpaste, 75ml 4.9 out of 5 stars 12 7 offers from SAR 33.95 Colgate Sensitive Pro Relief Base Instant Sensitivity Relief Toothpaste, 75ml 4.3 out of 5 stars 20 5 offers from SAR 31.25 Colgate Total 12 hour Protection Pro - Gum Health Toothpaste 75ml 2020;12(2):87. Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . The datasets analysed during the current study are available from the corresponding author on reasonable request. and Ayad et al. It effectively occludes open dentine tubuli instantly* and builds a strong calcium-rich layer that ensures long-lasting relief from the pain of sensitivity.1,2 The protective layer remains strong even after exposure to acid attacks.3, of respondents confirmed reduced dentine hypersensitivity with Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents were happy with their dentists recommending Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents noticed long-lasting and instant* relief when brushing with Colgate SENSITIVE INSTANT Relief toothpaste7,, Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. The maximum sampling time was 15min. *with direct application and daily brushing. Aust Dent J. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. 2016;27(4):916. Manage cookies/Do not sell my data we use in the preference centre. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity.
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